/* Patient navigation layer. Local fonts; no third-party requests. */
:root{--ink:#183b36;--muted:#516b64;--line:#d9e3dd;--paper:#fafbf8;--soft:#eef4ee;--accent:#246553;--accent-dark:#184b3c;--warm:#95542e;--white:#fff}
html{scroll-padding-top:116px}body{font-family:system-ui,-apple-system,BlinkMacSystemFont,"Segoe UI",sans-serif;color:var(--ink);background:var(--paper);font-size:18px;line-height:1.7}
*,*::before,*::after{box-sizing:border-box}a,button,input,summary{touch-action:manipulation}button,input,select{font:inherit}button{cursor:pointer}a{color:var(--accent-dark)}a:hover{text-decoration-thickness:2px}a:focus-visible,button:focus-visible,input:focus-visible,summary:focus-visible{outline:3px solid #a95718;outline-offset:4px}img{max-width:100%;height:auto}[hidden]{display:none!important}h1,h2,h3{color:var(--ink);text-wrap:balance}h2,h3{scroll-margin-top:112px}p{max-width:76ch}button{min-height:44px}.skip-link:focus{z-index:1000}
.site-header{padding:16px max(24px,calc((100vw - 1220px)/2));min-height:86px;gap:20px;background:#fafbf8f5;backdrop-filter:blur(12px);border-bottom:1px solid var(--line)}.brand{gap:12px;min-width:0}.brand-mark{width:44px;height:46px;border-radius:4px 14px 4px 14px;background:var(--accent-dark);flex-shrink:0;font-family:Georgia,serif;font-size:21px;font-weight:400}.brand strong{font-size:15px;line-height:1.35}.brand small{font-size:12px;line-height:1.5;margin-top:4px}.site-nav{gap:6px;font-size:14px}.site-nav a{padding:10px 11px;border-radius:6px;font-weight:600;color:var(--ink)}.site-nav a:hover,.site-nav a[aria-current]{background:#e9f0e8;text-decoration:none}.nav-toggle{width:70px;min-height:46px;border:1px solid var(--line);background:white;font-size:15px;display:none}
.home-page,.page{width:min(1160px,calc(100% - 64px));margin-inline:auto;padding:32px 0 72px}.eyebrow{color:var(--accent);font-size:12px;font-weight:750;letter-spacing:.12em;text-transform:uppercase}.new-home .intro-layout{display:grid;grid-template-columns:minmax(0,1.35fr) minmax(310px,.85fr);gap:56px;align-items:start;padding:38px 0 34px}.new-home h1{font-family:Georgia,"Times New Roman",serif;font-weight:400;font-size:clamp(2.4rem,4.5vw,4rem);line-height:1.12;letter-spacing:-.035em;margin:16px 0 24px}.new-home h1 em{font-weight:400;font-style:normal;color:var(--accent)}.intro-copy>.lead{font-size:19px;line-height:1.7;max-width:49ch;margin:0 0 24px}.intro-label{display:flex;align-items:center;gap:9px}.intro-label::before{content:"";width:20px;height:2px;background:var(--accent)}
.new-search{border:1px solid #bfd0c2;border-radius:10px;background:#fff;padding:18px 20px;max-width:none;width:100%}.new-search label{font-size:15px;color:var(--ink);display:block;margin:0 0 9px;font-weight:650}.search-row{display:flex;gap:8px}.search-row input{border:1px solid #a5bcae;border-radius:5px;min-height:50px;width:100%;min-width:0;padding:11px 12px;font-size:16px;background:#fff}.search-row button{border:0;border-radius:5px;padding:10px 20px;background:var(--accent-dark);color:#fff;font-weight:650}.search-hint{font-size:12px!important;line-height:1.5;margin:9px 0 0;color:var(--muted)}.suggestions{display:flex;gap:6px 14px;flex-wrap:wrap;font-size:13px;margin-top:14px}.suggestions a{padding:2px 0;text-underline-offset:3px}.search-results{width:100%;max-width:none;margin:16px 0 0}.search-results .search-hit{display:block;padding:14px 0;border-bottom:1px solid var(--line);text-decoration:none}.search-hit strong,.search-hit span{display:block}.search-hit strong{font-size:16px}.search-hit span{font-size:13px;color:var(--muted);line-height:1.6;margin-top:3px}.search-hit:hover strong{text-decoration:underline}.search-count{font-size:13px;color:var(--muted);margin:0 0 10px}.search-results ul{list-style:none;margin:0;padding:0}.search-results li{margin:0}.search-fallback{font-size:14px}
.path-panel{padding:26px;border:1px solid var(--line);border-radius:12px;background:#f0f4ed}.path-panel h2{font-size:19px;font-weight:650;margin:0 0 18px}.path-panel a{display:grid;grid-template-columns:34px 1fr 15px;align-items:center;gap:10px;padding:17px 0;border-top:1px solid #d4dfd0;text-decoration:none;min-height:72px}.path-panel a:last-child{padding-bottom:0}.path-panel a:hover strong{text-decoration:underline;text-underline-offset:4px}.path-panel strong{font-size:16px;line-height:1.3}.path-panel small{display:block;font-size:13px;color:var(--muted);margin-top:3px}.path-number{font-family:Georgia,serif;font-size:22px;color:#658172}.arrow{font-size:20px;font-weight:400}
.home-alert{margin:4px 0 0;padding:16px 20px;background:#fff4e8;border:1px solid #efd9c2;border-left:4px solid #9c511e;border-radius:4px;color:#713d19;font-size:14px;display:flex;gap:8px 16px;flex-wrap:wrap;align-items:center}.home-alert strong{font-size:15px}.home-alert a{color:#713d19;font-weight:650}.home-alert span{flex:1;min-width:220px}.home-alert .alert-icon{font-size:18px;flex:0;min-width:0}
.new-home .home-section{padding-top:52px}.section-top{display:flex;justify-content:space-between;align-items:end;gap:20px;margin-bottom:20px}.section-top h2{font-family:Georgia,serif;font-size:30px;font-weight:400;line-height:1.25;margin:5px 0 0;letter-spacing:-.015em}.section-top p{margin:0;font-size:14px;color:var(--muted)}.section-top>a{font-size:14px;flex-shrink:0;text-underline-offset:4px}.card-row{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:16px}.guide-card{display:flex;flex-direction:column;padding:24px;background:#fff;border:1px solid var(--line);border-radius:9px;text-decoration:none;min-height:192px;transition:background .15s,border-color .15s}.guide-card:hover{border-color:#7da18d;background:#f5f8f2}.guide-card .card-label{color:var(--accent);font-size:11px;font-weight:700;letter-spacing:.1em;text-transform:uppercase}.guide-card strong{font-size:21px;line-height:1.35;font-weight:650;margin:10px 0 9px;letter-spacing:-.02em}.guide-card p{font-size:15px;color:var(--muted);margin:0;line-height:1.6}.guide-card .card-tail{font-size:14px;display:flex;justify-content:space-between;margin-top:auto;padding-top:18px;color:var(--accent)}
.cancer-grid{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));border-top:1px solid var(--line);border-left:1px solid var(--line)}.cancer-grid a{display:flex;justify-content:space-between;align-items:center;gap:15px;border-bottom:1px solid var(--line);border-right:1px solid var(--line);padding:18px;font-size:16px;font-weight:600;text-decoration:none;background:#fff;min-height:67px}.cancer-grid a:hover{background:var(--soft)}.cancer-grid a span:last-child{font-weight:400;color:#637f70}.care-band{padding:30px 34px;display:grid;grid-template-columns:1fr 1fr;gap:32px;align-items:center;background:#eaf0e7;border-radius:10px}.care-band h2{font-family:Georgia,serif;font-size:30px;font-weight:400;margin:7px 0 14px;line-height:1.25}.care-band p{font-size:16px;margin:0}.care-links{display:grid;gap:8px}.care-links a{background:#fff;padding:12px 16px;border:1px solid #d2dfce;border-radius:5px;display:flex;justify-content:space-between;font-size:15px;text-decoration:none}.care-links a:hover{text-decoration:underline}.editorial-row{display:grid;grid-template-columns:1fr 1fr;gap:22px}.editorial-card{display:grid;grid-template-columns:124px 1fr;gap:20px;align-items:center;text-decoration:none;border:1px solid var(--line);border-radius:8px;padding:18px;background:white}.editorial-card img{width:124px;height:124px;object-fit:cover;border-radius:5px}.editorial-card time,.editorial-card small{font-size:12px;color:var(--muted);display:block}.editorial-card strong{display:block;font-size:19px;line-height:1.35;margin:6px 0}.editorial-card p{margin:0;font-size:14px;line-height:1.5;color:var(--muted)}.editorial-card:hover strong{text-decoration:underline}.trust-band{display:grid;grid-template-columns:1fr 1.2fr;gap:36px;border-top:1px solid var(--line);padding-top:32px;margin-top:48px}.trust-band h2{font-size:21px;margin:6px 0}.trust-band p{font-size:15px;margin:8px 0}.trust-links{display:flex;gap:18px;flex-wrap:wrap;font-size:14px}
.page h1{font-size:clamp(1.9rem,3.2vw,2.8rem);letter-spacing:-.025em;line-height:1.22}.page-hero{max-width:860px;margin-bottom:26px}.page-hero>.lead,.page-hero>p:last-child{font-size:18px;line-height:1.75}.breadcrumbs{font-size:13px;margin:0 0 28px;display:flex;flex-wrap:wrap;gap:8px;line-height:1.6}.breadcrumbs a{min-height:24px}.breadcrumbs span[aria-current]{max-width:68ch}.page .article-body{max-width:840px;border:0;padding:0;background:transparent;box-shadow:none}.page .article-body>p,.page .article-body>ul,.page .article-body>ol{max-width:72ch}.article-body h2{margin-top:40px;padding-top:10px;font-size:26px}.article-body h3{font-size:21px;margin-top:28px}.page p,.page li{color:#36564b}.page .content-section{margin-top:36px}.page-meta{font-size:13px}.notice,.archive-notice{font-size:15px;line-height:1.7}.notice a{font-weight:600}.article-tools{margin:22px 0;font-size:14px}.article-tools a{padding:8px 0}.toc{max-width:840px;border-radius:7px;background:#eef3ec;padding:14px 20px}.toc summary{padding:3px;font-size:15px}.toc ol{columns:2;column-gap:30px;font-size:14px;margin:14px 0 5px;padding-left:24px}.toc li{break-inside:avoid;padding:4px}.toc a{display:inline-block;line-height:1.5}.quick-links{position:static;display:flex;flex-wrap:wrap}.quick-links a{font-size:14px;min-height:44px;padding:10px 15px}.table-wrap{overflow:auto;border:1px solid var(--line);border-radius:7px;max-width:100%;margin:24px 0}.table-wrap table{font-size:15px;width:100%;border-collapse:collapse;min-width:580px}.table-wrap th{background:var(--soft);text-align:left}.table-wrap th,.table-wrap td{padding:12px 16px;border-bottom:1px solid var(--line);vertical-align:top}.related-grid a{padding:20px;border-radius:7px}.reading-help{max-width:840px;margin:30px 0;font-size:13px;border-top:1px solid var(--line);border-bottom:1px solid var(--line);padding:12px 0;display:flex;flex-wrap:wrap;gap:8px 18px}.reading-help a{padding:2px 0}
.catalogue-controls{padding:22px;background:var(--soft);border:1px solid var(--line);border-radius:9px;max-width:none}.catalogue-controls label{font-weight:650;display:block;font-size:15px;margin-bottom:9px}.catalogue-controls input{padding:13px 15px;width:100%;min-height:50px;font-size:17px;border:1px solid #9bb7a4;border-radius:5px;background:white}.filter-buttons{display:flex;flex-wrap:wrap;gap:7px;margin:15px 0}.filter-buttons button{font-size:13px;min-height:44px;padding:8px 13px;border:1px solid #adc2b0;color:var(--ink);background:white;border-radius:5px}.filter-buttons button[aria-pressed=true]{background:var(--accent-dark);color:white;border-color:var(--accent-dark)}.js-only{display:none}.js .js-only{display:block}.js .filter-buttons.js-only{display:flex}.category-jumps{display:flex;flex-wrap:wrap;gap:6px 18px;margin:18px 0;font-size:14px}.category-jumps a{padding:8px 0}.catalogue-section{margin:34px 0}.catalogue-section h2{font-family:Georgia,serif;font-weight:400;font-size:26px}.catalogue-section .catalogue-list{display:grid;grid-template-columns:1fr 1fr;gap:0 24px;list-style:none;padding:0}.catalogue-list li{border-top:1px solid var(--line);padding:16px 0;min-width:0}.catalogue-list a{display:block;text-decoration:none}.catalogue-list strong{font-size:16px;line-height:1.5;display:block}.catalogue-list span{display:block;font-size:14px;color:var(--muted);margin-top:4px;line-height:1.65}.catalogue-list a:hover strong{text-decoration:underline}.catalogue-count{font-size:14px;margin:14px 0 0}.empty-search{padding:24px;border:1px solid var(--line);background:#fff;border-radius:6px;margin-top:20px}.empty-search p{font-size:16px}.empty-search button{padding:8px 16px;border:1px solid var(--accent);background:#fff;border-radius:4px;color:var(--accent-dark)}.drug-index{grid-template-columns:repeat(3,minmax(0,1fr))}.drug-card{min-height:0;border-radius:7px}.drug-card p{font-size:15px}.drug-card h2{font-size:22px}.drug-card a{font-size:15px;min-height:44px;padding-top:10px}.drug-search-intro{margin:0 0 25px}.drug-search-intro .suggestions{font-size:14px}
.site-footer{background:#173c32;color:#f0f4ed;padding:38px max(24px,calc((100vw - 1160px)/2));grid-template-columns:1.2fr 1fr;gap:22px 40px}.site-footer strong{color:#fff}.site-footer p{color:#d6e2d7;font-size:14px}.site-footer a{color:#eef5ea;font-size:14px;text-underline-offset:4px;min-height:32px}.site-footer .footer-note{font-size:12px;max-width:100%;border-color:#476256;color:#d6e2d7}.site-footer .footer-note a{font-size:12px}.site-footer nav{gap:5px 22px}.back-top{border-radius:6px}
@media(max-width:1200px){.site-header{flex-wrap:wrap;padding:14px 24px}.site-nav{position:static;display:flex;flex-direction:row;width:100%;justify-content:flex-start;flex-wrap:wrap;box-shadow:none;padding:0;border:0;background:transparent;gap:3px}.js .site-nav{display:none}.js .site-nav.is-open{display:flex}.nav-toggle{display:block;margin-left:auto}.new-home .intro-layout{gap:30px}.site-nav a{font-size:15px;padding:10px 14px}}
@media(min-width:1201px){.site-nav{display:flex!important}.nav-toggle{display:none!important}}
@media(max-width:850px){.new-home .intro-layout{grid-template-columns:1fr;padding-top:18px;gap:24px}.new-home h1{max-width:15ch;font-size:clamp(2.5rem,6vw,3.5rem)}.intro-copy>.lead{max-width:58ch}.path-panel{padding:20px 24px}.path-panel a{padding:13px 0;min-height:64px}.path-panel a:last-child{padding-bottom:2px}.card-row{grid-template-columns:1fr 1fr}.card-row .guide-card:last-child{grid-column:1/-1;min-height:unset}.cancer-grid{grid-template-columns:1fr 1fr}.editorial-row{grid-template-columns:1fr}.care-band{grid-template-columns:1fr;gap:24px}.trust-band{grid-template-columns:1fr;gap:12px}.drug-index{grid-template-columns:1fr 1fr}.page-meta{grid-template-columns:1fr}.toc ol{columns:1}}
@media(max-width:560px){html{scroll-padding-top:100px}.site-header{padding:12px 16px;gap:10px;min-height:76px}.brand-mark{width:36px;height:39px;font-size:17px}.brand strong{font-size:13px;max-width:190px}.brand small{font-size:10px}.brand{gap:9px}.nav-toggle{width:57px;font-size:14px}.site-nav a{padding:10px;font-size:14px}.home-page,.page{width:calc(100% - 32px);padding:24px 0 48px}.new-home h1{font-size:40px;line-height:1.14;margin:12px 0 19px}.new-home .intro-layout{padding:6px 0 20px}.intro-copy>.lead{font-size:17px}.new-search{padding:16px}.new-search label{font-size:14px}.search-row input{font-size:16px;padding:10px;min-height:48px}.search-row button{padding:10px 14px;font-size:15px}.path-panel{padding:18px}.path-panel h2{font-size:17px}.path-panel strong{font-size:15px}.path-panel small{font-size:12px}.home-alert{padding:14px 16px;font-size:13px;gap:4px 10px}.home-alert span{flex-basis:100%;min-width:0}.home-alert .alert-icon{display:none}.new-home .home-section{padding-top:36px}.section-top{align-items:start;margin-bottom:16px;gap:10px}.section-top h2{font-size:26px}.section-top>a{font-size:12px;max-width:100px;flex-shrink:1}.section-top p{font-size:12px}.card-row{grid-template-columns:1fr;gap:12px}.guide-card{padding:20px;min-height:unset}.guide-card strong{font-size:20px}.guide-card p{font-size:14px}.guide-card .card-tail{padding-top:12px}.cancer-grid a{font-size:14px;padding:13px;min-height:65px}.care-band{padding:24px}.care-band h2{font-size:27px}.care-band p{font-size:15px}.editorial-card{grid-template-columns:82px 1fr;gap:14px;padding:14px}.editorial-card img{width:82px;height:100px}.editorial-card strong{font-size:17px}.editorial-card p{font-size:13px}.trust-band{margin-top:36px}.catalogue-controls{padding:16px}.filter-buttons button{font-size:12px;padding:8px 11px}.catalogue-section .catalogue-list{grid-template-columns:1fr}.catalogue-list strong{font-size:16px}.catalogue-list span{font-size:14px}.drug-index{grid-template-columns:1fr}.page h1{font-size:30px}.page .article-body{padding:0}.page .article-body h2{font-size:24px}.page-hero>.lead,.page-hero>p:last-child{font-size:17px}.breadcrumbs{font-size:12px;line-height:1.7;gap:4px 7px;margin-bottom:20px}.site-footer{grid-template-columns:1fr;padding:30px 20px}.article-tools{font-size:13px;gap:8px 18px}.related-grid{grid-template-columns:1fr}.table-wrap table{font-size:14px}.search-hint{font-size:12px!important}}
@media(prefers-reduced-motion:reduce){html{scroll-behavior:auto}*,*::before,*::after{transition:none!important;animation:none!important}}
@media print{.site-header,.site-footer,.new-search,.catalogue-controls,.filter-buttons,.article-tools,.toc,.reading-help,.category-jumps{display:none!important}.home-page,.page{width:100%;padding:0}.catalogue-section,.catalogue-list li{display:block!important}.article-body p,.page p,.page li{color:#000}.card-row,.editorial-row,.intro-layout,.trust-band,.catalogue-section .catalogue-list{display:block!important}.guide-card,.editorial-card,.path-panel,.care-band{break-inside:avoid;margin:12px 0}.table-wrap{overflow:visible}.table-wrap table{min-width:0}.breadcrumbs{display:none}.home-alert{break-inside:avoid}h2,h3{break-after:avoid}}

.blood-figure{margin:28px 0;max-width:620px}.blood-figure img{display:block;width:100%;height:auto;border:1px solid var(--line);border-radius:12px}.blood-figure figcaption{font-size:14px;line-height:1.6;color:var(--muted);margin-top:10px}.blood-guide{border-top:1px solid var(--line);border-bottom:1px solid var(--line);padding-bottom:24px}.blood-guide>h2{font-size:28px}.source-ref{font-size:.7em;white-space:nowrap}.source-ref a{padding:3px}.content-updated{font-size:14px!important}.recent-guides .card-row{grid-template-columns:repeat(2,minmax(0,1fr))}.recent-guides .guide-card{min-height:0}.recent-guides .guide-card strong{font-size:19px}.fragment-alias{scroll-margin-top:120px}.table-wrap:focus-visible{outline:3px solid #a95718;outline-offset:4px}.suggestions a,.category-jumps a,.reading-help a,.trust-links a,.site-footer nav a{display:inline-flex;align-items:center;min-height:44px}.breadcrumbs a{padding-block:8px;min-height:40px}.table-wrap:focus-within{border-color:#a95718}@media(max-width:560px){.recent-guides .card-row{grid-template-columns:1fr}.blood-figure{margin:24px 0}.blood-guide>h2{font-size:24px}}